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PF Small-Angle X-ray Scattering Beamline
PF小角散乱ビームライン
高エネルギー加速器研究機構
    物質構造科学研究所


〒305-0801 茨城県つくば市大穂1-1

メンバー業績リストHEADLINE


2024年 2023年 2022年 2021年 2020年 2019年 2018年 2017年 2016年 2015年 2014年 2013年 2012年 2011年

2024年

2023年

  • Mahmoud, N. H. M., Takagi, H., Shimizu, N., Igarashi, N. and Sakurai, S.

    Significantly High Melting Temperature of Homopolymer Crystals Obtained in a Poly(l-Lactic Acid)/Poly(d-Lactic Acid) (50/50) Blend.
    ACS Omega 8, 40482-40493 (2023). https://doi.org/10.1021/acsomega.3c05165

  • Otsuka, C., Takahashi, S., Isobe, A., Saito, T., Aizawa, T., Tsuchida, R., Yamashita, S., Harano, K., Hanayama, H., Shimizu, N., Takagi, H., Haruki, R., Liu, L., Hollamby, M. J., Ohkubo, T. and Yagai, S.

    Supramolecular Polymer Polymorphism: Spontaneous Helix?Helicoid Transition through Dislocation of Hydrogen-Bonded π-Rosettes.
    J. Am. Chem. Soc. 145, 22563-22576 (2023). https://doi.org/10.1021/jacs.3c07556

  • Shimokawa, M., Ishiwata, A., Kashima, T., Nakashima, C., Li, J., Fukushima, R., Sawai, N., Nakamori, M., Tanaka, Y., Kudo, A., Morikami, S., Iwanaga, N., Akai, G., Shimizu, N., Arakawa, T., Yamada, C., Kitahara, K., Tanaka, K., Ito, Y., Fushinobu, S. and Fujita, K.

    Identification and characterization of endo-α-, exo-α-, and exo-β-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria.
    Nat. Commun. 14, 5803 (2023). https://doi.org/10.1038/s41467-023-41431-2

    ・東京大学大学院農学生命科学研究科ニュース

  • Jiang, X., Ogawa, T., Yonezawa, K., Shimizu, N., Ichinose, S., Uchihashi, T., Nagaike, W., Moriya, T., Adachi, N., Kawasaki, M., Dohmae, N., Senda, T. and Hirokawa, N.

    The two‐step cargo recognition mechanism of heterotrimeric kinesin.
    EMBO Rep. e56864 (2023). https://doi.org/10.15252/embr.202356864

  • Watanabe, Y., Ogawa, H., Konishi, T., Nishitsuji, S., Ono, S., Shimizu, N. and Takenaka, M.

    Distribution of Oriented Lamellar Structures in Injection-Molded High-Density Polyethylene Visualized via SAXS-CT Method.
    Macromolecules 56, 5964-5973 (2023). https://doi.org/10.1021/acs.macromol.3c00731

  • Takagi, H., Nakano, T., Aoki, T. and Tanimoto, M.

    The structural changes of a bovine casein micelle during temperature change; in situ observation over a wide spatial scale from nano to micrometer.
    Soft Matter 19, 4562-4570 (2023).https://doi.org/10.1039/d3sm00146f

  • Qin, XY., Furutani, Y., Yonezawa, K., Shimizu, N., Kato-Murayama, M., Shirouzu, M., Xu, Y., Yamano, Y., Wada, A., Gailhouste, L., Shresttha, R., Takahashi, M., Keillor, J. W., Su, T., Yu, W., Fujii, S., Kagechika, H., Dohmae, N., Shirakami, Y., Shimizu, M., Masaki, T., Matsuura, T., Suzuki., S. and Kojima, S.

    Targeting transglutaminase 2 mediated exostosin glycosyltransferase 1 signaling in liver cancer stem cells with acyclic retinoid.
    Cell Death Dis. 14, 358 (2023). https://doi.org/10.1038/s41419-023-05847-4
    ・理化学研究所とKEK共同のプレスリリース

  • 清水 伸隆

    BioSAXS を活用した生体高分子の溶液構造状態推定
    日本結晶学会誌 65, 42-50 (2023).https://doi.org/10.5940/jcrsj.65.42

  • Yonezawa, K., Takahashi, M.,Yatabe, K., Nagatani, Y. and Shimizu, N.

    MOLASS: Software for automatic processing of matrix data obtained from small-angle X-ray scattering and UV-visible spectroscopy combined with size-exclusion chromatography.
    Biophys. Physicobiol. 20, e200001 (2023). https://doi.org/10.2142/biophysico.bppb-v20.0001  

2022年

  • Osumi, R., Yasui, T., Tanaka, R., Mai, T. -T., Takagi, H., Shimizu, N., Tsunoda, K., Sakurai, S. and Urayama, K.

    Impact of Strain-Induced Crystallization on Fast Crack Growth in Stretched cis-1,4-Polyisoprene Rubber.
    ACS Macro Lett. 11, 747-752 (2022). doi:https://doi.org/10.1021/acsmacrolett.2c00241

  • Miwa, Y., Ohya, T., Takagi, H. and Kutsumizu, S.

    In Situ SAXS Observation of Transient Network Behavior in Ionically Cross-Linked Polydimethylsiloxane Elastomer with Slow and Fast Stretching.
    Macromolecules 55, 9126-9133 (2022). doi:https://doi.org/10.1021/acs.macromol.2c01737

  • Oka, M., Takagi, H., Orie, A. and Honda, S.

    Realizing Vat-Photocycloaddition 3D Printing with Recyclable Synthetic Photorheological Silicone Fluids.
    Macromol. Rapid Commun. 43, 2200407 (2022). doi:https://doi.org/10.1002/marc.202200407

  • Suzuki, R., Li, L., Imoto, H., Takagi, H., Sakurai, S. and Naka, K.

    Single-component optically transparent film of a star-shaped cage silsesquioxane derivative and its phase change behavior.
    Polym. J. 54, 1179-1190 (2022). doi:https://doi.org/10.1038/s41428-022-00674-4

  • Doi, T., Takagi, H., Shimizu, N., Igarashi, N. and Sakurai, S.

    Shear-Strained Structures Induced during Hot-Melt Coating and Their Gradual Temporal Changes in Coated Layers Composed of Block Copolymer/Tackifier Blends.
    ACS Appl. Polym. Mater. 4, 4886-4900 (2022). doi:https://doi.org/10.1021/acsapm.2c00484

  • Takahashi, D., Yonezawa, K., Okizaki, Y., Caaveiro, J. M. M., Ueda, T., Shimada, A., Sakane, F. and Shimizu, N.

    Ca2+-induced structural changes and intramolecular interactions in N-terminal region of diacylglycerol kinase alpha.
    Protein Sci. 31, e4365 (2022). doi:https://doi.org/10.1002/pro.4365

  • Takagi, H., Nakano, T., Aoki, T. and Tanimoto, M.

    Temperature dependence of the casein micelle structure in the range of 10-40 ℃: An in-situ SAXS study.
    Food Chem. 393, 133389 (2022). doi:https://doi.org/10.1016/j.foodchem.2022.133389

  • 高木 秀彰, 中野 智木, 清水 伸隆, 青木 孝良, 谷本 守正

    Reconsideration of a structural model of a casein micelle for small-angle X-ray scattering measurements.
    日本酪農科学会誌 71, 10-22 (2022). doi:https://doi.org/10.11465/milk.71.10

  • Virk, K., Yonezawa, K., Choukate, K., Singh, L., Shimizu, N. and Chaudhuri, B.

    K-edge anomalous SAXS for protein solution structure modeling.
    Acta Crystallogr. Sect. D-Biol. Crystallogr. 78, 204-211 (2022).
    doi:https://doi.org/10.1107/S205979832101247X

2021年

  • Tashiro, K., Katayama, K., Tamaki, K., Pesce, L., Shimizu, N., Takagi, H., Haruki, R., Hollamby, M. J., Pavan, G. M. and Yagai, S.

    Non-uniform Photoinduced Unfolding of Supramolecular Polymers Leading to Topological Block Nanofibers.
    Angew. Chem.-Int. Edit. 60, 26986-26993 (2021). doi:https://doi.org/10.1002/anie.202110224

  • 太田 昇, 高木 秀彰, 増永 啓康, 関口 博史, 清水 伸隆

    放射光小角X線散乱装置
    めそん 54, 17-26 (2021). http://jmeson.org/2021/11/29/post-955/

  • Tanaka, R., Kabe, T., Masunaga, H., Takagi, H., Shimizu, N., Igarashi, N. and Sakurai, S.

    Relationship between formation of kink structure and necking of a specimen comprising hard and soft lamellar microdomains under uniaxial stretching.
    材料 70, 17-24 (2021). doi:https://doi.org/10.2472/jsms.70.17

  • Doi, T., Takagi, H., Shimizu, N., Igarashi, N. and Sakurai, S.

    Stress-Strain and Stress-Relaxation Behaviors of Solution-Coated Layers Composed of Block Copolymers Mixed with Tackifiers.
    ACS Omega 6, 17299 (2021). doi:https://doi.org/10.1021/acsomega.1c01367

  • Takagi, H. and Yamamoto, K.

    Effect of Block Copolymer Composition and HomopolymerMolecular Weight on Ordered Bicontinuous Double-DiamondStructures in Binary Blends of Polystyrene-Polyisoprene BlockCopolymer and Polyisoprene Homopolymer.
    Macromolecules 54, 5136-5143 (2021). doi:https://doi.org/10.1021/acs.macromol.1c00429

  • Oka, M., Takagi, H., Miyazawa, T., Waymouth, R. M. and Honda, S.

    Photocleavable Regenerative Network Materials with Exceptional and Repeatable Viscoelastic Manipulability.
    Adv. Sci. 8, 2101143 (2021). doi:https://doi.org/10.1002/advs.202101143

  • Pandey, A. K., Takagi, H., Igarashi, N., Shimizu, N. and Sakurai, S.

    Enhanced formation of stereocomplex crystallites in Poly(L-lactic acid)/ Poly(D-lactic acid) blends by silk fibroin nanodisc.
    Polymer 229, 124001 (2021). doi:https://doi.org/10.1016/j.polymer.2021.124001

  • Banpean, A., Takagi, H., Shimizu, N., Igarashi, N. and Sakurai, S.

    Small- and Wide-Angle X-ray Scattering Studies on Confined Crystallization of Poly(ethylene glycol) in Poly(L-lactic acid) Spherulite in a PLLA/PEG Blend.
    Polymer 229, 123971 (2021). doi:https://doi.org/10.1016/j.polymer.2021.123971

  • Fukushima, T., Tamaki, K., Isobe, A., Hirose, T., Shimizu, N., Takagi, H., Haruki, R., Adachi, S., Hollamby, M. J. and Yagai, S.

    Diarylethene-Powered Light-Induced Folding of Supramolecular Polymers.
    J. Am. Chem. Soc.143, 5845-5854 (2021). doi:https://doi.org/10.1021/jacs.1c00592

    板橋 大輔, 村尾 玲子, 谷口 俊介, 水上 和実, 高木 秀彰, 木村 正雄

    非対称流れ流動場分離(AF4)法によるナノ粒子の粒子径分布測定
    鉄と鋼 107, 82-91 (2021). doi:https://doi.org/ 10.2355/tetsutohagane.TETSU-2020-088

  • Yamamoto, K. and Takagi, H.

    Frank-Kasper σ and A-15 Phases Formed in Symmetry and Asymmetry Block Copolymer Blend System.
    Mater. Trans. 62, 325 (2021). doi:https://doi.org/10.2320/matertrans.MT-MB2020002

  • Hamamoto, H., Takagi, H., Akiba, I. and Yamamoto, K.

    Analysis of Homopolymer Distribution in a Polymer Blend Thin Film by Anomalous Grazing Incidence Small-Angle X-ray Scattering at the Bromine K-Edge.
    Macromolecules 54, 488-498 (2021). doi:https://doi.org/10.1021/acs.macromol.0c02017


2020年

  • Doi, T., Takagi, H., Shimizu, N., Igarashi, N. and Sakurai, S.

    Effects of Solubility Difference of Tackifier to Respective Components of Block Copolymers on Microphase-Separated Structures in Coated Layers of Pressure-Sensitive Adhesive Prepared by Solution Coating Process.
    ACS Appl. Polym. Mater. 2, 4973-4984 (2020). doi:https://doi.org/10.1021/acsapm.0c00845

  • Toma-Fukai, S., Hibi, R., Naganuma, T., Sakai, M., Saijo, S., Shimizu, N., Matsumoto, M. and Shimizu, T.

    Crystal structure of GCN5 PCAF N-terminal domain reveals atypical ubiquitin ligase structure.
    J. Biol. Chem. 295, 14630-14639 (2020). doi:https://doi.org/10.1074/jbc.RA120.013431

  • Sum, J. S., Yamazaki, Y., Yoshida, K., Yonezawa, K., Hayashi, Y., Kataoka, M. and Kamikubo, H.

    Spectroscopic and structural characteristics of a dual-light sensor protein, PYP-phytochrome related protein.
    Biophys. Physicobiol. 17, 103-112 (2020). doi:https://doi.org/10.2142/biophysico.BSJ-2020015

  • Nagano, Y., Sugiyama, A., Kimoto, M., Wakahara, T., Noguchi, Y., Jiang, X.,Saijo, S., Shimizu, N. , Yabuno, N., Yao, M., Gooley, P. R., Moseley, G .W., Tadokoro, T., Maenaka, K. and Ose, T.

    The measles virus V protein binding site to STAT2 overlaps with that of IRF9.
    J. Virol. 94 (2020). doi:https://doi.org/10.1128/JVI.01169-20

  • Sasaki, N., Mabesoone, M. F. J., Kikawa, J., Fukui, T., Shioya, N., Shimoaka, T., Hasegawa, T., Takagi, H. , Haruki, R., Shimizu, N. , Adachi, S., Meijer, E. W., TAkeuchi, M. and Sugiyasu, H.

    Supramolecular double-stranded Archimedean spirals and concentric toroids.
    Nat. Commun. 11, 3578 (2020). doi:https://doi.org/10.1038/s41467-020-17356-5

  • Hirai, M., Ajito, S., Iwase, T., Wen, D., Igarashi, N. and Shimizu, N.

    Short-Distance Intermolecular Correlations of Mono- and Disaccharides in Condensed Solutions: Bulky Character of Trehalose.
    ACS Omega. 5, 10815-10825 (2020). doi: https//doi.org/10.1021/acsomega.0c00451

  • 米澤 健人,清水 伸隆

    ゲル濾過クロマトグラフィーと組み合わせたタンパク質X線溶液散乱解析技術
    生物物理 60, 180-184 (2020). doi: https//doi.org/10.2142/biophys.60.180

  • Doi, T., Takagi, H., Shimizu, N., Igarashi, N. and Sakurai, S.

    Effects of drying temperature in solution coating process on the structural changes upon uniaxial stretching of sphere-forming block copolymer films.
    Polym. J. 52, 421-433 (2019). doi: 10.1038/s41428-019-0287-z

  • Aratsu, K., Takeya, R., Pauw, B. R., Hollamby, M. J., Kitamoto, Y., Shimizu, N., Takagi, H., Haruki, R., Adachi, S., Yagai, S.

    Supramolecular copolymerization driven by integrative self-sorting of hydrogen-bonded rosettes.
    Nat. Commun. 11, 1623 (2020). doi: 10.1038/s41467-020-15422-6
          
    千葉大学とKEK共同のプレスリリース

  • Ite, K., Yonezawa, K., Kitanishi, K., Shimizu, N., and Unno, M.

    Optimal Mutant Model of Human S100A3 Protein Citrullinated at Arg51 by Peptidylarginine Deiminase Type III and Its Solution Structural Properties.
    ACS Omega 5, 4032-4042 (2020). doi: 10.1021/acsomega.9b03618


2019年

  • Pham, T. N. D., Takagi, H., Shimizu, N., Igarashi, N., Sasaki, S. and Sakurai, S.

    Effects of Loading Amount of Plasticizers on Improved Crystallization of Poly (L-lactic acid).
    Journal of Fiber Science and Technology 75,99-111 (2019). doi: 10.2115/fiberst.2019-0013

  • Hirata, A., Okada, K., Yoshii, K., Shiraishi, H., Saijo, S., Yonezawa, K., Shimizu, N. and Hori, H.

    Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition.
    Nucleic Acids Res. 47, 10942-10955 (2019). doi: 10.1093/nar/gkz856

    愛媛大学とKEK共同のプレスリリース

  • Kitamoto, Y., Pan, Z., Prabhu, D. D., Isobe, A., Ohba, T., Shimizu, N., Takagi, H., Haruki, R., Adachi, S. and Yagai, S.

    One-shot preparation of topologically chimeric nanofibers via a gradient supramolecular copolymerization.
    Nat. Commun. 10, 4578 (2019). doi: 10.1038/s41467-019-12654-z

    千葉大学のプレスリリース
    物構研トピックス

  • Suzuki, A., Aratsu, K., Datta, S., Shimizu, N., Takagi, H., Haruki, R., Adachi, S., Hollamby, M., Silly, F. and Yagai, S.

    Topological Impact on the Kinetic Stability of Supramolecular Polymersc nanofibers via a gradient supramolecular copolymerization.
    J. Am. Chem. Soc. 141, 13196-13202 (2019). doi: 10.1021/jacs.9b06029

  • Pandey, A. K., Katiyar, V., Takagi, H., Shimizu, N., Igarashi, N., Sasaki, S. and Sakurai, S.

    Structural Evolution in Isothermal Crystallization Process of Poly(L-lactic acid) Enhanced by Silk Fibroin Nano-Disc.
    Materials 12, 1872 (2019). doi: 10.3390/ma12111872

  • Doi, T,. Takagi, H., Shimizu, N., Igarashi, N. and Sakurai, S.

    Effects of drying temperature in solution coating process on microphase-separated structures in coated layers of pressure-sensitive adhesive composed of di- and triblock copolymer blends as revealed by small-angle X-ray scattering.
    Polymer 170, 211-221 (2019). doi: https://doi.org/10.1016/j.polymer.2019.02.052

  • Miyamoto, T., Hayashi, Y., Yoshida, K., Watanabe, H., Uchihashi, T., Yonezawa, K., Shimizu, N., Kamikubo, H. and Hirota, S.

    Construction of a Quadrangular Tetramer and a Cage-Like Hexamer from Three-Helix Bundle-Linked Fusion Proteins.
    ACS Synth. Biol. 8, 1112-1120 (2019). doi: 10.1021/acssynbio.9b00019

  • Hirai, M., Ajito, S., Takahashi, K., Iwasa, T., Li, X., Wen, D., Kawai-Hirai, R., Ohta, N., Igarashi, N. and Shimizu, N.

    Structure of Ultrafine Bubbles and Their Effects on Protein and Lipid Membrane Structures Studied by Small- and Wide-Angle X-ray Scattering.
    J. Phys. Chem. B 123, 3421-3429 (2019). doi: 10.1021/acs.jpcb.9b00837

  • Takagi, H., Hashimoto, R., Igarashi, N., Yamamoto, K., Kishimoto, S.

    High spatial resolution small angle X-ray scattering experiments using SOPHIAS detector.
    Nucl. Instrum. Methods Phys. Res. A 924, 417-421 (2019). doi: https://doi.org/10.1016/j.nima.2018.09.073

  • 高木秀彰, 山本勝宏

    ブロック共重合体/ブロック共重合体ブレンドの球状ミクロドメインが作る最密充填格子
    高分子論文集 76, 157-162 (2019). doi: https://doi.org/10.1295/koron.2018-0048

  • Takagi, H. and Yamamoto, Y.

    Phase Boundary of Frank-Kasper σ Phase in Phase Diagrams of Binary Mixtures of Block Copolymers and Homopolymers.
    Macromolecules 52, 2007-2014 (2019). doi: 10.1021/acs.macromol.8b02356

  • Pham, T. N. D., Mochizuki, M., Doi, M., Takagi, H., Shimizu, N., Igarashi, N., Sasaki, S. and Sakurai, S.

    Effects of a special diluent as an agent of improving the crystallizability of poly(L-lactic acid).
    Polym. J. 51, 283-294 (2019). doi: https://doi.org/10.1038/s41428-018-0152-5

  • Yonezawa, K., Takahashi, M., Yatabe, K., Nagatani, Y. and Shimizu, N.

    Software for serial data analysis measured by SEC-SAXS/UV-Vis spectroscopy.
    AIP Conf. Proc. 2054, 060082 (2019). doi: 10.1063/1.5084713

  • Takagi, H., Igarashi, N., Nagatani, Y., Ohta, H., Mori, T., Kosuge, T. and Shimizu, N.

    New high-brilliance small angle x-ray scattering beamline, BL-15A2 at the photon factory.
    AIP Conf. Proc. 2054, 060038 (2019). doi: 10.1063/1.5084669

  • Igarashi, N., Takagi, H., Ohta, H., Mori, T., Tomita, S., Nagatani, Y., Kosuge, T., Okuda, H. and Shimizu, N.

    Further developments of the tender x-ray diffractometer at BL-15A2 of the photon factory.
    AIP Conf. Proc. 2054, 060043 (2019). doi: 10.1063/1.5084674

  • Shimizu, N., Mori, T., Nagatani, Y., Ohta, H., Saijo, S., Takagi, H., Takahashi, M., Yatabe, K., Kosuge, T. and Igarashi, N.

    BL-10C, the small-angle x-ray scattering beamline at the photon factory.
    AIP Conf. Proc. 2054, 060041 (2019). doi: 10.1063/1.5084672

  • Honda, S., Oka, M., Takagi, H. and Toyota, T.

    Topology‐Reset Execution: Repeatable Postcyclization Recyclization of Cyclic Polymers.
    Angew. Chem. Int. Ed. 58, 144 - 148 (2019). doi: 10.1002/anie.201809621

    東京大学とKEK共同のプレスリリース

  • Kobayashi, C., Kato, M., Nagaya, H., Shimizu, N., Ishibashi, K., Ishikawa, M. and Katoh, E.

    Purification and functional characterization of tomato mosaic virus130K protein expressed in silkworm pupae using a baculovirus vector.
    Protein Expr. Purif. 154, 85-90 (2019). doi: https://doi.org/10.1016/j.pep.2018.10.001

2018年

  • Bayomi, R. A. H., Honda, K., Wataoka, I., Takagi, H., Shimizu, N., Igarashi, N., Sasaki, S. and Sakurai, S.

    Grain coarsening on the free surface and in the thickness direction of a sphere-forming triblock copolymer film.
    Polym. J. 50, 1029-1042 (2018). doi: 10.1038/s41428-018-0094-y

  • Hirai, M., Ajito, S., Iwase, H., Takata, SI., Ohta, N., Igarashi, N. and Shimizu, N.

    Restoration of Myoglobin Native Fold from Its Initial State of Amyloid Formation by Trehalose.
    J. Phys. Chem. B 122, 11962-11968 (2018). doi: 10.1021/acs.jpcb.8b09379

  • Hashimoto, R., Igarashi, N., Kumai, R., Takagi, H., Kishimoto, S., Kudo, T. and Hatsui, T.

    Application of the SOPHIAS Detector to Synchrotron Radiation X-Ray Experiments.
    Springer Proc. in Phys. 213, 263-266 (2018). doi: 10.1007/978-981-13-1316-5_49

  • Kajikawa, M., Ose, T., Fukunaga, Y., Okabe, Y., Matsumoto, N., Yonezawa, K., Shimizu, N., Kollnberger, S., Kasahara, M. and Maenaka, K.

    Structure of MHC class I-like MILL2 reveals heparan-sulfate binding and interdomain flexibility.
    Nat. commun. 9, 4330 (2018). doi: 10.1038/s41467-018-06797-8

  • Hirai, M., Ajito, S., Sato, S., Ohta, N., Igarashi, N. and Shimizu, N.

    Preferential Intercalation of Human Amyloid-β Peptide into Interbilayer Region of Lipid-Raft Membrane in Macromolecular Crowding Environment.
    J. Phys. Chem. B 122, 9482-9489 (2018). doi: 10.1021/acs.jpcb.8b08006

  • Konno, S., Banno, T., Takagi, H., Honda, S. and Toyota, T.

    Irreversible aggregation of alternating tetra-block-like amphiphile in water.
    PLoS One 13, e0205140. (2018). doi: https://doi.org/10.1371/journal.pone.0202816

  • Prabhu, D. D., Aratsu, K., Kitamoto, Y., Ouchi, H., Ohba, T., Hollamby, M. J., Shimizu, N., Takagi, H., Haruki, R., Adachi, S. and Yagai, S.

    Self-folding of supramolecular polymers into bioinspired topology.
    Sci. Adv. 4, eaat8466 (2018). doi: 10.1126/sciadv.aat8466
    ・自発的に折りたたまれるポリマー材料の開発に成功(プレスリリース)

  • Hirai, M., Ajito, S., Sugiyama, M., Iwase, H., Takata, S., Shimizu, N., Igarashi, N., Martel, A. and Porcar, L.

    Direct Evidence for the Effect of Glycerol on Protein Hydration and Thermal Structural Transition.
    Biophys. J. 115, 313-327 (2018). doi: https://doi.org/10.1016/j.bpj.2018.06.005

  • Fujii, H., Tanaka, Y., Nakazawa, H., Sugiyama, A., Manabe, N., Shinoda, A., Shimizu, N., Hattori, T., Hosokawa, K., Sujino, T., Ito, T., Niide, T., Asano, R., Kumagai, I. and Umetsu, M.

    Compact Seahorse-Shaped T Cell-Activating Antibody for Cancer Therapy.
    Adv. Therap. 1700031 (2018). doi: https://doi.org/10.1002/adtp.201700031

  • Bayomi, R. A. H., Aoki, T., Shimojima, T., Takagi, H., Shimizu, N., Igarashi, N., Sasaki, S. and Sakurai, S.

    Structural analyses of sphere- and cylinder-forming triblock copolymer thin films near the free surface by atomic force microscopy, X-ray photoelectron spectroscopy, and grazing-incidence small-angle X-ray scattering.
    Polymer 147, 202-212 (2018). doi: https://doi.org/10.1016/j.polymer.2018.05.074

  • Takagi, H. and Yamamoto, K.

    Close-packed structures of the spherical microdomains in block copolymer-homopolymer binary mixture.
    Trans. Mat. Res. Soc. Japan 43, 161-165 (2018). doi: https://doi.org/10.14723/tmrsj.43.161

  • Takagi, H., Hashimoto, R., Igarashi, N., Kishimoto, S. and Yamamoto, K.

    Synchrotron SAXS Studies on Lattice Structure of Spherical Micelles in Binary Mixtures of Block Copolymers and Homopolymers.
    Journal of Fiber Science and Technology 74, 10-16 (2018). doi: https://doi.org/10.2115/fiberst.2018-0002

  • Ajito, S., Hirai, M., Iwase, H., Shimizu, N., Igarashi, N. and Ohta, N.

    Protective action of trehalose and glucose on protein hydration shell clarified by using X-ray and neutron scattering.
    Phys. B Condens. Matter. 551, 249-255 (2018). doi: https://doi.org/10.1016/j.physb.2018.03.040

  • Hirai, M., Ajito, S., Sugiyama, M., Iwase, H., Takata, S., Shimizu, N., Igarashi, N., Martel, A. and Porcar, L.

    Macromolecular crowding effect on protein structure and hydration clarified by using X-ray and neutron scattering.
    Phys. B Condens. Matter. 551, 212-217 (2018). doi: https://doi.org/10.1016/j.physb.2018.02.020

  • Bernadó, P., Shimizu, N., Zaccai, G., Kamikubo, H. and Sugiyama, M.

    Solution scattering approaches to dynamical ordering in biomolecular systems.
    BBA - General Subjects 1862, 253-274 (2018). doi: https://doi.org/10.1016/j.bbagen.2017.10.015


     

2017年

  • 清水伸隆, 浴本 亨, 穴見康昭, 伊藤俊将, 池口満徳, 山本恵子

    MD-SAXS法によるビタミンD受容体リガンド結合ドメインの不活性型および活性阻害型の溶液構造解析
    放射光 30, 264-276 (2017).

  • Yamanaka, R., Shimizu, N., Igarashi, N., Takagi, H. and Sakurai, S.

    Orienting cylindrical microdomains in polystyrene-b-poly(ethylene-co-butylene)-b-polystyrene triblock copolymer/diluent sheet by application of temperature gradient
    Polimery 62, 812-820 (2017). doi: 10.14314/polimery.2017.812

  • Chen, M., Kato, K., Kubo, Y., Tanaka, Y., Liu, Y., Long, F., Whitman, W. B., Lill, P., Gatsogiannis, C., Raunser, S., Shimizu, N., Shinoda, A., Nakamura, A., Tanaka, I. and Yao, M.

    Structural basis for tRNA-dependent cysteine biosynthesis.
    Nat commun. 8, 1521 (2017). doi: 10.1038/s41467-017-01543-y

  • Nojima, S., Fujishima, A., Kato, K., Ohuchi, K., Shimizu, N., Yonezawa, K., Tajima, K. and Yao, M.

    Crystal structure of the flexible tandem repeat domain of bacterial cellulose synthesis subunit C.
    Sci. Rep. 7, 13018 (2017). doi: 10.1038/s41598-017-12530-0.

  • Ogawa, T., Saijo, S., Shimizu, N., Jiang, X. and Hirokawa, N.

    Mechanism of Catalytic Microtubule Depolymerization via KIF2-Tubulin Transitional Conformation.
    Cell Reports 20, 2626-2638 (2017). doi: http://dx.doi.org/10.1016/j.celrep.2017.08.067.

    東京大学とKEK共同のプレスリリース

  • Yonezawa, K., Shimizu, N., Kurihara, K., Yamazaki, Y., Kamikubo, H. and Kataoka, M.

    Neutron crystallography of photoactive yellow protein reveals unusual protonation state of Arg52 in the crystal.
    Sci. Rep. 7, 9361 (2017). doi: 10.1038/s41598-017-09718-9.

  • Shimizu, H., Toma-Fukai, S., Saijo, S., Shimizu, N., Kontani, K., Katada, T. and Shimizu, T.

    Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding.
    J. Biol. Chem. 292, 13441-13448 (2017). doi: 10.1074/jbc.M117.792556.

  • Tomita, S., Shimizu, N., Igarashi, N., Takagi, H., Sasaki, S. and Sakurai, S.

    Time-resolved 2d-SAXS measurements to reveal mechanism of cylinder orientation upon sphere-to-cylinder transition under a planar flow in an SEBS triblock copolymer sheet.
    Eur. Polym. J. 93, 382-389 (2017). https://doi.org/10.1016/j.eurpolymj.2017.05.033

  • Tomita, S., Wataoka, I., Igarashi, N., Shimizu, N., Takagi, H., Sasaki, S. and Sakurai, S.

    Strain-Induced Deformation of Glassy Spherical Microdomains in Elastomeric Triblock Copolymer Films: Time-Resolved 2d-SAXS Measurements under Stretched State.
    Macromolecules 50, 3404-3410 (2017).

  • Adhikari, B., Yamada, Y., Yamauchi, M., Wakita, K., Lin, X., Aratsu, K., Ohba, T., Karatsu, T., Hollamby, M., Shimizu, N., Takagi, H., Haruki, R., Adachi, S. and Yagai, S.

    Light-induced unfolding and refolding of supramolecular polymer nanofibres.
    Nat. Commun. 8, 15254 (2017). doi: 10.1038/ncomms15254

    千葉大学とKEK共同のプレスリリース

  • Tomita, S., Shimizu, N., Igarashi, N., Takagi, H., Sasaki, S. and Shinichi Sakurai, S.

    Coalescence of non-equilibrium spheres through thermal annealing in a polystyrene-block-poly(ethylene-co-butylene)-block-polystyrene triblock copolymer film under a uniaxially stretched state.
    Polymer Journal 49, 519-526 (2017). doi: 10.1038/pj.2017.9

  • Yamauchi, M., Adhikari, B., Prabhu, D. D., Lin, X., Karatsu, T., Ohba, T., Shimizu, N., Takagi, H., Haruki, R., Adachi, S., Kajitani, T., Fukushima, T. and Yagai, S.

    Supramolecular Polymerization of Supermacrocycles: Effect of Molecular Conformations on Kinetics and Morphology.
    Chem. Eur. J. 23, 5270-5280 (2017). doi: 10.1002/chem.201605873

  • Adachi, N., Aizawa, K., Kratzer, Y., Saijo, S., Shimizu, N. and Senda, T.

    Improved method for soluble expression and rapid purification of yeast TFIIA.
    Protein Expr. Purif. 133, 50-56 (2017). doi: 10.1016/j.pep.2017.02.013

  • Takagi, H., Hashimoto, R., Igarashi, N., Kishimoto, S. and Yamamoto, K.

    Frank-Kasper sigma phase in polybutadiene-poly(epsilon-caprolactone) diblock copolymer / polybutadiene blends.
    J. Phys. : Condens. Matter 29, 204002 (2017).

  • Abe, R., Nagoshi, K., Arai, T., Watanabe, S., Sano, Y., Matsuura, H., Takagi, H., Shimizu, N., Koka, M. and Sato, T.       

    Microscopic analyses of complexes formed in adsorbent for Mo and Zr separation chromatography. Nucl. Instr. Meth. Phys. Res. B 404, 173-178 (2017). https://doi.org/10.1016/j.nimb.2017.02.082

  • Takagi, H., Takasaki, T. and Yamamoto, K.

    Phase Diagram for Block Copolymer and Homopolymer Blends: The Phase Boundary of the OBDD Network Structure.
    J. Nanosci. Nanotechnol. 17, 9009-9014 (2017).


2016年

  • Takagi, H., Igarashi, N., Mori, T., Saijo, S., Nagatani, Y., Ohta, H., Yamamoto, K. and Shimizu, N.

    Structural analysis of polymer thin films using GISAXS in the tender X- ray region: Concept and design of GISAXS experiments using the tender X- ray energy at BL-15A2 at the Photon Factory.
    J. Appl. Phys. 120, 142119 (2016).

  • 高木秀彰

    放射光X線小角散乱法によるブロック共重合体/ホモポリマーブレンドが形成する新種ミクロ相分離構造に関する研究
    繊維学会誌 72, 431-435 (2016).

  • Kubota, M., Takeuchi, K., Watanabe, S., Ohno, S., Matsuoka, R., Kohda, D., Nakakita, S., Hiramatsu, H., Suzuki, Y., Nakayama, T., Terada, T., Shimizu, K., Shimizu, N., Shiroishi, M., Yanagi, Y. and Hashiguchi, T.

    Trisaccharide containing α2,3-linked sialic acid acid is a receptor for mumps virus.
    Proc. Natl. Acad. Sci. USA 113, 11579-11584 (2016).

    物構研トピックス   
    九州大学発表のプレスリリース

  • Anami, Y., Shimizu, N., Ekimoto, T., Egawa, D., Itoh, T., Ikeguchi, M. and Yamamoto, K.

    Apo- and antagonist-binding structures of vitamin D receptor ligand-binding domain revealed by hybrid approach combining small-angle X-ray scattering and molecular dynamics.
    J. Med. Chem. 59, 7888-7900 (2016).

    KEK発表のプレスリリース

  • Yamada, A., Shimizu, N., Hikima, T., Takata, M., Kobayashi, T. and Takahashi, H.

    Effect of Cholesterol on the Interaction of Cytochrome P450 Substrate Drug Chlozoxazone with the Phosphatidylcholine Bilayer.
    Biochemistry 55, 3888-3898 (2016).

  • Hashimoto, R., Arai, Y., Igarashi, N., Kumai, R., Miyoshi, T. and Kishimoto, S.

    Test results of a counting type SOI device for a new x-ray area detector.
    AIP Conf. Proc. 1741, 040031 (2016).

  • Igarashi, N., Nitani, H., Takeichi, Y., Niwa, Y., Abe, H., Kimura, M., Mori, T., Nagatani, Y., Kosuge, T., Kamijo, A., Koyama, A., Ohta, H. and Shimizu, N.

    Newly designed double surface bimorph mirror for BL-15A of the Photon Factory.
    AIP Conf. Proc. 1741, 040021 (2016).

  • Shimizu, N., Yatabe, K., Nagatani, Y., Saijyo, S., Kosuge, T. and Igarashi, N.

    Software Development for Analysis of Small-angle X-ray Scattering Data.
    AIP Conf. Proc. 1741, 050017 (2016).

  • Takagi, H., Igarashi, N., Mori, T., Saijyo, S., Ohta, H., Nagatani, Y., Kosuge, T. and Shimizu, N.

    Upgrade of Small Angle X-ray Scattering Beamline, BL-6A at the Photon Factory.
    AIP Conf. Proc. 1741, 030018 (2016).

  • Saijyo, S., Nagai, A., Kinjo, S., Mashimo, R., Akimoto, M., Kizawa, K., Yabe-Wada, T., Shimizu, N., Takahara, H. and Unno, M.

    Monomeric Form of Peptidylarginine Deiminase Type I Revealed by X-ray Crystallography and Small-Angle X-ray Scattering.
    J. Mol. Biol. 428, 3058-3073 (2016).

  • Takagi, H., Sugino, Y., Hara, S. Yamamoto, K. and Shimada, S.

    Non-equilibrium disordered micelles observed after melting of crystalline-amorphous alternating lamellar structure in crystalline-amorphous block copolymers forming spherical morphology.
    Colloid Polym Sci 294, 993-999 (2016).

  • Saito, I., Shimada, D., Aikawa, M., Miyazaki, T., Shimokita, K., Takagi H. and Yamamoto, K.

    Orientation and relaxation behaviors of lamellar micro-domains of poly(methyl methacrylate)-b-poly(n-butyl acrylate) thin film as revealed by grazing-incidence small angle X-ray scattering.
    Polymer Journal 48, 399-406 (2016).

  • Toma-Fukai, S., Kim, J. D., Park, K. E., Kuwabara, N., Shimizu, N., Krayukhina, E., Uchiyama, S., Fukamizu, A. and Shimizu, T.

    Novel helical assembly in arginine methyltransferase 8.
    J. Mol. Biol. 428, 1197-1208 (2016).

  • Rahman, S., Yamato, I., Saijo, S., Mizutani, K., Takamuku, Y., Ishizuka-Katsura, Y., Ohsawa, N., Terada, T., Shirouzu, M., Yokoyama, S. and Murata, T.

    Binding interactions of the peripheral stalk subunit isoforms from human V-ATPase.
    Biosci. Biotechnol. Biochem. 80, 878-890 (2016).


2015年

  • The, A. H., Makino, M., Hoshino, T., Baba, S., Shimizu, N., Yamamoto, M. and Kumasaka, T.

    Structure of the RsbX phosphatase involved in the general stress response of Bacillus subtilis.
    Acta Cryst. D71, 1392-1399 (2015).
     

  • Hirai, M., Sato, S., Kimura, R., Hagiwara, Y., Kawai-Hirai, R., Ohta, N., Igarashi, N. and Shimizu, N.

    Effect of encapsulation of proteins on thermal stability of lipid liposome composed of glycosphingolipd, cholesterol, and phospholipid.
    J. Phys. Chem. B 119, 3398-3406 (2015).

  • Takagi, H., Yamamoto, K. and Okamoto, S.

    Ordered-bicontinuous-double-diamond structure in block copolymer / homopolymer blends.
    EPL (Europhysics Letters) 110, 48003 (2015).

  • Takagi, H., Yamamoto, K., Okamoto, S. and Sakurai, S.

    A study on the phase behavior of poly(e-caprolactone)-poly(butadiene) diblock copolymers: The influence of relatively low-molecular-weight block copolymers on the order-disorder transition behavior.
    Polymer 67, 20-27 (2015).

  • Oberta, P., Kittler, M., A?, V., Hrdy, J., Iragashi, N., Scheinost, A. C. and Uchida, Y.

    The influence of metallic brazing materials on the strain formation of internally water-cooled X-ray optics.
    J. Synchrotron Rad. 22, 342-347 (2015).

2014年

  • Tiena, N. D., Sasaki, S., Masunaga, H., Shimizu, N., Igarashi, N. and Sakurai, S.

    Small-Angle X-ray Scattering Studies on Melting and Recrystallization Behaviors of Poly(oxyethylene) Crystallites in Poly(d,l-lactide) / Poly(oxyethylene) Blends.
    Polymer 55, 2562-2569 (2014).


2013年

  • Alam, M. J., Yamato, I., Arai, S., Saijo, S., Mizutani, K., Ishizuka-Katsura, Y., Ohsawa, N., Terada, T., Shirouzu, M., Yokoyama, S., Iwata, S., Kakinuma, Y. and Murata, T.

    Mutant LV(476-7)AA of A-subunit of Enterococcus hirae V1-ATPase: High affinity of A3B3 complex to DF axis and low ATPase activity.
    Springerplus 2, 689 (2013).

  • Alam, M. J., Arai, S., Saijo, S., Suzuki, K., Mizutani, K., Ishizuka-Katsura, Y., Ohsawa, N., Terada, T., Shirouzu, M., Yokoyama, S., Iwata, S., Kakinuma, Y., Yamato, I. and Murata, T.

    Loose binding of the DF axis with the A3B3 complex stimulates the initial activity of Enterococcus hirae V1-ATPase.
    PLoS One 8, e74291 (2013).

  • Shimizu, N., Shimizu, T., Baba, S., Hasegawa, K., Yamamoto, M. and Kumasaka, T.

    Development of an online UV-visible microspectrophotometer for the macromolecular crystallography beamline.
    J. Synchrotron Rad. 20, 948-952 (2013).

  • Hasegawa, K., Shimizu, N., Okumura, H., Mizuno, N., Baba, S., Hirata, K., Takeuchi, T., Yamazaki, H., Senba, Y., Ohashi, H., Yamamoto, M. and Kumasaka, T.

    SPring-8 BL41XU, a high flux macromolecular crystallography beamline.
    J. Synchrotron Rad. 20, 910-913 (2013).

  • Hirai, M., Kimura, R., Takeuchi, K., Hagiwara, Y., Kawai-Hirai, R., Ohta, N., Igarashi, N. and Shimizu, N.

    Structure of liposome encapsulating proteins characterized by X-ray scattering and shell-modeling.
    J. Synchrotron Rad. 20, 869-874 (2013).

  • Igarashi, N., Shimizu, N., Koyama, A., Mori, T., Ohta, H., Niwa, Y., Nitani, H., Abe, H., Nomura, M., Shioya, T., Tsuchiya, K. and Ito, K.

    New high-brilliance beamline BL-15A of the Photon Factory.
    J. Phys.: Conf. Ser. 425,072016 (2013).

  • Shimizu, N., Mori, T., Igarashi, N., Ohta, H., Nagatani, Y., Kosuge, T. and Ito, K.

    Refurbishing of Small-Angle X-ray Scattering Beamline, BL-6A at the Photon Factory.
    J. Phys.: Conf. Ser. 425, 202008 (2013).

      

2012年

  • Makino, M., Wada, I., Mizuno, N., Hirata, K., Shimizu, N., Hikima, T., Yamamoto, M. and Kumasaka, T.

    Fine-needle capillary mounting for protein microcrystals.
    J. Appl. Cryst. 45, 785-788 (2012).

  • Gai, Z., Kitagawa, Y., Tanaka, Y., Shimizu, N., Komoda, K., Tanaka, I. and Yao, M.

    The binding mechanism of eIF2β with its partner proteins, eIF5 and eIF2βε.
    Biochem. Biophys. Res. Commun. 423, 515-519 (2012).

  • Murakami, H., Ueno, G., Shimizu, N., Kumasaka, T. and Yamamoto, M.

    Upgrade of automated sample exchanger SPACE.
    J. Appl. Cryst. 45, 239-244 (2012).

2011年

  • Iino, H., Shimizu, N., Goto, M., Ebihara, A., Fukui, K., Hirotsu, K. and Kuramitsu, S.

    Crystal Structure of the Tandem-type Universal Stress Protein TTHA0350 from Thermus thermophilus HB8.
    J. Biochem. 150, 295-302 (2011).

  • Iwasaki, T., Kappl, R., Bracic, G., Shimizu, N., Ohmori, D. and Kumasaka, T.

    ISC-like [2Fe-2S] ferredoxin (FdxB) dimer from Pseudomonas putida JCM 20004: structural and electron-nuclear double resonance characterization.
    J. Biol. Inorg. Chem. 16, 923-935 (2011).

  • Igarashi, N., Watanabe, Y., Shinohara, Y., Inoko, Y., Matsuba, G., Okuda, H., Mori, T. and Ito, K.

    Upgrade of the small angle X-ray scattering beamlines at the Photon Factory
    J. Phys.: Conf. Ser. 272, 012026 (2011).